The only FDA approved over the counter weight loss pill, Alli is more than just a pill. It is a complete weight loss program designed to work with you, not for you. Using Alli, consumers can lose up to 50% more weight than with diet and exercise alone, but you have to change the way you eat. It combines individualized plans for success with a powerful fat blocker. Alli works in your digestive system, rather than in the heart or brain. Alli requires you to commit to it. Alli retails for $59.99.